DISORDER provides tools for simulation of the diffraction patterns from fibrillar assemblies of biomolecules and optimization of the fibrillar models with respect to experimental diffraction data. Examples of the program application include building of fibrillar molecular structures, simulation of the diffraction patterns for this structures, visual and quantitative comparison of the simulated and experimental diffraction data. A scripting language implemented in DISORDER allows user to automate the search for the models of fibrillar assemblies which provide the best fit to the observed diffraction data.

System Requirement
Currently DISORDER runs on Microsoft Windows and Linux (Mac OS X version is not tested and available upon request). A Pentium 4 or faster processor is essential for a simulation to be done in minutes. A minimum of 200MB free RAM is usually needed to avoid significant performance deterioration.

Downloads and Installation
Click here to download DISORDER. The tar package contains DISORDER executables (disorder.exe for Windows and disorder.x for Linux), documentation and test examples. To display calculated diffraction patterns, you will need either FIT2D or WCEN.

Quick Notes         What's New         Manual and tutorial:  Word  PDF